Safe House is a character-driven psychological thriller with a strong investigative narrative, inspired by true events. Each season sees a new cast and a new case, all centering on a police safe house coming under threat.

Suave, smart, and somewhat strange, Raphaël Balthazar (Tomer Sisley) can make the dead speak like no one else. As a forensic pathologist in Paris, he works with no-nonsense chief inspector Hélène Bach (Hélène de Fougerolles) to solve the city's most disturbing crimes. But there's one case that continues to haunt him--the murder of his wife over a decade ago.